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4th Annual Meeting, 129Xe MRI Clinical Trials Consortium, 2019
 
The Betsy Hotel, South Beach, Miami, Florida
23-25 January 2019
 
Welcome to the registration site for the 4th Annual Meeting of the 129Xe MRI Clinical Trials Consortium,
23-25 January 2019 at The Betsy Hotel in South Beach, Miami, Florida!
For more information about the Consortium, please go to: https://cpir.cchmc.org/XeMRICTC
 
Please click the "Registration" tab above for meeting fees & registration.  
We look forward to seeing you in South Beach!

DRAFT AGENDA: 10 December 2018
 
Item/Topic
 Presenter/Facilitator
Wednesday, 1/23/19
Please plan to arrive at the Betsy before 16:00   
 
  16:00
Welcome, Opening Remarks, Introductions
 Jason Woods
  16:10-16:30
Experience as the first 129Xe site with regulatory approval
Jim Wild
  16:35-17:00
A long and tortuous highway: the route to approval by FDA
Ken West
  17:00-1715
Discussion and questions
 
  17:15
Reception and continued discussion
 
  18:00
 Dinner
 
Thursday, 1/24/19
Location (TBD)
 
  08:00-08:30
           Breakfast (buffet)
 
  08:30-08:40
Brief introduction to agenda and day
Jason Woods
  08:40-10:40
Latest and Greatest, with focus on improved patient management (12m each)
Sheffield (1.47° W)
Virginia (78.47° W)
Duke (78.93° W)
Toronto (79.38° W)
London, ON (81.24° W)
Cincinnati (84.51° W)
Wisconsin (89.41° W)
Missouri (92.33° W)
In order of longitude
 
Jim Wild
 
 
 
Grace Parraga
Laura Walkup
Sean Fain
Robert Thomen
  10:40-10:50
Discussion & Break (10 mins)
 
  10:50-11:15
Preparing for break-out sessions. What is the most impactful thing we can measure, and in what disease?Framing the problem for Asthma, CF, COPD, PVD and ILDs (5m each)
All-physician panel, facilitated by Loretta Que
 
Business meeting
 
  11:15-11:30
Harmonizing quality control: First results, phantom
Bastiaan Driehuys
  11:30-11:45
Generic MRI protocol for clinical trials.Are we there?
John Mugler
  11:45-11:55
Xe makes it a clinical trial?A humorous NIH due process
Zackary Cleveland
  12:00-13:10
Lunch
 
  13:15-13:30
The NIH foundation biomarker consortium
Bastiaan Driehuys
  13:30-13:45
Adverse-event harmonization and reporting
Lisa, Joanne?
  13:45-14:00
Image repository, built in parallel to first studies. Can CF HyPOINT study be the test run of central analysis? Need funds to sustain…
Jason Woods
  14:00-14:15
Governance:  Changes to document:  Funding, database access, Harmonization documents?
Sean Fain
 
Break (10 mins)
 
 
Disease and trial-focused sessions
 
 
Cystic Fibrosis
 
  14:25-14:35
Clinical background: Times They Are A Changin’: therapeutics on the near horizon
Felix Ratjen
  14:35-14:50
Opportunity for 129Xe MRI: That Old tyme ventilation
Giles Santyr
  14:50-15:05
Clinical Trial: The HyPOINT trial proposal (CF Foundation)
Jason Woods
  15:05-15:30
Implementation panel (all research coordinators, nurses)
Facilitators: Kelly, Erin
  15:40-16:30
Refreshments and group Discussion by disease (3):What is the most impactful thing we can measure, and how well do we need to measure it?
3 Groups split by disease:asthma & CF, COPD, PVD & ILDs
 All
  16:30-17:00
Reporting (10m per disease group)
 
  17:00-17:30
Break (10 mins)
 
  17:30-18:00
Meet at Hotel Lobby, walk to dinner
 
  18:00
 Dinner         
 
 
Item/Topic
 Presenter
Friday, 1/25/19
Location (TBD)
 
   08:00-08:30
            Breakfast (buffet)
 
 
Chronic obstructive pulmonary disease
 
   08:30-08:40
Clinical background:   Treatments for COPD:  EB valves and newer therapeutics
Frank McCormack
   08:43-08:53
Opportunity for 129Xe MRI:  Placing valves and measuring efficacy
Jaime Mata
   08:55-09:05
Clinical Trial: Ideas for EB valves
Loretta Que
 
            Discussion (20 mins)
 
 
Adult and pediatric asthma
 
   09:25-09:35
Clinical background: It’s the biologics, stupid
Loretta Que
   09:37-09:47
Clinical background: You mean kids aren’t just little adults?
Nancy Lin
   09:49-10:03
Opportunity for 129Xe MRI: Predicting asthma exacerbations, treatment response
Sarah Svenningsen
   10:05-10:15
Clinical Trial: Multi-site asthma trial (NIH+Sanofi ?)
Sean Fain
 
            Discussion (20 mins)
 
 
            Break (10 mins)
 
 
ILDs and PVD  Perhaps include/separate PVD
 
   10:45-10:57
Clinical background: Is everything else called an ILD?
Bruce Trapnell
   10:58-11:08
Opportunity for 129Xe MRI: PVD – Could the cardiologists be our beach-head into imaging centers?
Bastiaan Driehuys
   11:10-11:20
What can we learn from MIGET in how we present our imaging data?”
Tony Huang
 
            Open Discussion (15 mins)
 
   11:35-12:00
Action Items, Closing Remarks, Meeting Evaluation
Jason Woods
   12:00-1:00
           Lunch
 
   13:00
Close of the 2019 129Xe MRI Clinical Trials Consortium meeting
 
 
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